Quick answer
- Federal drug schedules
- Amanita muscaria, muscimol and ibotenic acid are not listed (21 CFR Part 1308)
- FDA on food
- Not authorized as an ingredient in conventional food (December 18, 2024)
- FDA on supplements
- Warning letters in 2025 and 2026 called amanita supplements adulterated
- Louisiana
- Products for human consumption containing muscimol or ibotenic acid are banned (from August 1, 2025)
Federal drug law
Amanita muscaria, the red and white fly agaric mushroom, contains muscimol and ibotenic acid. None of the three is listed in the federal schedules of controlled substances, 21 CFR Part 1308, as of November 2026. The Controlled Substances Act does not cover it.
It is not a cannabis product, so the federal hemp change of December 11, 2026 does not apply to it either.
What the FDA has said
On December 18, 2024 the FDA said Amanita muscaria and certain of its constituents (muscimol, ibotenic acid and muscarine) are "not authorized for use as ingredients in conventional food." It called them unapproved food additives, and said in a letter to industry that food containing them is adulterated.
The same notice said the FDA was also evaluating their use in dietary supplements. It has since sent warning letters to two companies about amanita products sold as supplements, on September 11, 2025 and September 29, 2026, each finding the products adulterated. As of November 5, 2026 we found no FDA rule on amanita in supplements.
Louisiana
Louisiana is the one state we found with a statute on amanita. R.S. 40:989.1 lists Amanita muscaria as a hallucinogenic plant and bars making or selling it in products intended for human consumption, and possessing it for that use. It allows it for decorative or landscaping purposes, in homeopathic drugs, and in products labeled as dietary supplements that meet specific federal requirements.
Act 154 of 2025 added R.S. 40:989.5, effective August 1, 2025. It bans any product intended for human consumption that contains muscimol, ibotenic acid, beta-phenyl-GABA or an analog of them. Its text has no exceptions.
We found no enacted amanita statute in any other state as of November 5, 2026. State law changes often, so check yours.
Functional mushrooms are a different thing
Lion's mane, reishi and cordyceps are culinary and functional mushrooms with no muscimol. Federal drug law does not list them, and the Louisiana laws above do not name them.
Related pages
Mushroom spores by state covers a different question: spores of psilocybin mushrooms. Psilocybin covers its federal status and the Oregon and Colorado programs.
Common questions
Is amanita muscaria a controlled substance?
Not under federal law. Amanita muscaria, muscimol and ibotenic acid do not appear in the federal schedules of controlled substances, 21 CFR Part 1308, as of November 2026.
What did the FDA say about amanita muscaria?
On December 18, 2024 the FDA said Amanita muscaria and its constituents muscimol, ibotenic acid and muscarine are not authorized for use as ingredients in conventional food, and that it was evaluating their use in dietary supplements. It has since sent warning letters to companies selling amanita supplements, in September 2025 and September 2026.
Which states restrict amanita muscaria?
Louisiana. Its law lists Amanita muscaria as a hallucinogenic plant and bars making or selling it for human consumption, with exceptions for decorative use, homeopathic drugs and certain dietary supplements. A 2025 law, R.S. 40:989.5, separately bans products intended for human consumption that contain muscimol, ibotenic acid or beta-phenyl-GABA.
Sources
- 21 CFR Part 1308, schedules of controlled substances, eCFR, National Archives
- FDA alerts industry and consumers about the use of Amanita muscaria or its constituents in food (December 18, 2024), U.S. Food and Drug Administration
- Letter to industry on the use of Amanita muscaria or its constituents in food, U.S. Food and Drug Administration
- Warning letter, CMS 711990 (September 11, 2025), U.S. Food and Drug Administration
- Warning letter, CMS 730137 (September 29, 2026), U.S. Food and Drug Administration
- Louisiana R.S. 40:989.1, hallucinogenic plants, Louisiana State Legislature
- Act 154 of 2025 (HB 176), enacting R.S. 40:989.5, Louisiana State Legislature
Each source was last read on November 5, 2026. Laws and rules change; check the source for the current text.